Spiritual Music and Mantra Practice as Adjuncts for Stress-Related Somatic Symptoms: A Case Report with Literature-Guided Discussion

Abstract

Introduction: Spiritual music and mantra chanting are widely used in South Asian cultural contexts for mind–body regulation, yet detailed clinical descriptions of their use for specific somatic complaints remain scarce. This report presents an individual with stress-related somatic symptoms who self-initiated spiritual music listening and "OM" mantra chanting alongside usual medical care, and discusses the observed changes against current evidence.
Case presentation: A 52-year-old woman presented with recurrent palpitations, chest tightness, and intermittent epigastric discomfort over six months. Repeated electrocardiography and abdominal ultrasonography revealed no structural abnormality. While continuing her unchanged low-dose antihypertensive regimen, she self-initiated 30 minutes of daily spiritual music listening followed by 20 minutes of "OM" mantra chanting for eight weeks. Pre- and post-intervention assessments showed: systolic blood pressure 132 → 124 mmHg; heart rate 78 → 70 beats/min; Perceived Stress Scale (PSS-10) score 24 → 16. She reported reduced palpitation frequency and improved sleep onset. No adverse events were reported.
Discussion: Available evidence suggests that mantra chanting and spiritual music can produce short-term reductions in heart rate and blood pressure and increases in heart rate variability, but these effects are concentrated at the level of autonomic modulation and stress reduction. There is no high-quality evidence supporting these practices as disease-modifying treatments for coronary artery disease, neurodegenerative disease, or structural intestinal disease. Health effects attributed to holy-city visits and river contact are currently limited to the psychological–spiritual domain, and environmental pollution risks warrant caution.
Conclusion: Spiritual music and mantra practice may serve as adjunctive tools for stress-related symptom management but should not replace standard evaluation and treatment of organic disease. Rigorous single-case experimental designs or randomized controlled trials are needed to clarify effect sizes and applicable populations.
Keywords: spiritual music; mantra; case report; stress; heart rate variability
1 Introduction
Spiritual music and mantra chanting have long histories of practice within South Asian cultural traditions and have increasingly entered the research purview of complementary and mind–body medicine. Small studies have reported that "OM" chanting can lower blood pressure and heart rate and increase heart rate variability (HRV) indices reflecting parasympathetic activity; Hare Krishna mantra meditation has likewise been reported to reduce stress indices. However, these studies have largely involved healthy volunteers or short-term laboratory settings, and detailed clinical descriptions of individuals using such practices for specific somatic complaints in real-life contexts remain scarce.
This case report aims to: (1) describe the experience and measurable changes in an individual whose chief complaints were palpitations, chest tightness, and epigastric discomfort, after routine investigations failed to identify a clear organic cause, and who self-initiated spiritual music and mantra practice; and (2) use this as a starting point to discuss, against current literature, the plausible role and clear boundaries of such practices in the management of cardiovascular, neurological, and digestive symptoms. The report follows the CARE guideline framework for case reports.
2 Case Presentation
2.1 Patient Information and Chief Complaint
The patient is a 52-year-old homemaker residing in an urban community, first seen in March 2025. Her chief complaint was recurrent "tightness in the chest and irregular heartbeat" for six months, accompanied by intermittent epigastric fullness and belching. Symptoms were most noticeable when alone or during quiet evenings, and worsened with fatigue or emotional fluctuation. She had no history of smoking or alcohol use. She had a three-year history of hypertension managed with amlodipine 5 mg/day, with blood pressure controlled in the 130–140/80–85 mmHg range.
2.2 History and Prior Evaluation
Because of palpitations, she underwent two resting electrocardiograms at a community hospital, both showing sinus rhythm without significant ST-T changes. A 24-hour Holter monitor showed occasional premature atrial contractions (<100/24 h) without sustained arrhythmia. Abdominal ultrasonography revealed no gallstones or evident organ abnormality. Gastroscopy indicated mild chronic non-atrophic gastritis. She declined further cardiac stress testing, requesting to "try something else first."
The patient reported having heard that spiritual music benefits "the heart and the brain," and in April 2025 she self-initiated a daily morning practice: approximately 30 minutes of listening to spiritual music (including traditional Indian instruments and chanting), followed by approximately 20 minutes of "OM" mantra chanting (alternating silent and vocal repetition). She made no changes to her medication regimen, diet, or exercise habits during the practice period. She kept a practice log, with family assistance confirming adherence.
2.3 Measurable Indicators Before and After Intervention
At baseline (before practice) and after eight weeks of continued practice, seated blood pressure and heart rate were measured by the same investigator in a quiet setting (three measurements averaged), and the patient completed the Perceived Stress Scale (PSS-10). Results were as follows:
| Indicator | Baseline (April 2025) | After 8 Weeks (June 2025) |
|---|---|---|
| Systolic BP (mmHg) | 132 | 124 |
| Diastolic BP (mmHg) | 82 | 78 |
| Heart rate (beats/min) | 78 | 70 |
| PSS-10 score | 24 | 16 |
Subjectively, the patient reported that palpitation frequency decreased from "almost daily" to "once or twice a week"; sleep onset latency shortened; epigastric discomfort showed no clear change, but she "minded it less." No dizziness, fatigue, or other adverse effects were reported. Acceptance of and adherence to the practice were good.
2.4 Timeline
March 2025: Initial consultation; electrocardiography and ultrasonography completed; no clear organic cause identified.
March–April 2025: Patient in observation; practice not yet initiated.
Early April 2025: Baseline measurements; PSS-10 = 24.
April–June 2025: Daily spiritual music 30 min + OM chanting 20 min; adherence approximately 85% (per log records).
June 2025: Follow-up measurements; PSS-10 = 16; blood pressure and heart rate reduced; subjective symptom improvement.
3 Discussion
3.1 Positioning of This Case
The core feature of this case is that the patient's complaints spanned cardiovascular (palpitations), digestive (epigastric discomfort), and psychological (perceived stress) domains, while routine investigations failed to establish organic disease sufficient to explain all symptoms. Against this background, the observable effects of the spiritual music and mantra practice she introduced were concentrated at the level of autonomic modulation and stress perception: reduced heart rate, mildly reduced blood pressure, and improved PSS-10 score. This is directionally consistent with prior findings on the short-term effects of OM chanting and mantra meditation on HRV and stress indices.
It must be stated clearly: this case cannot demonstrate that spiritual music "treated" heart disease, brain disease, or intestinal disease. The magnitude of heart rate and blood pressure change was small, the patient continued her antihypertensive medication unchanged, and natural fluctuation, seasonal variation, or placebo/expectancy effects cannot be excluded. The subjective report of "minding it less" regarding epigastric discomfort more likely reflects changed symptom tolerance following altered stress perception rather than pathological improvement of gastritis.
3.2 Comparison with Existing Evidence
Cardiovascular system: OM chanting and spiritual music have shown tendencies toward reduced heart rate and blood pressure and increased HRV in short-term studies. However, a randomized trial in patients with coronary artery disease found that a singing intervention improved microvascular endothelial function but did not change macrovascular function. This suggests that the effects of such practices may occur primarily at the microcirculatory and autonomic levels rather than directly altering the atherosclerotic process.
Brain and nervous system: Music interventions show potential for symptom management in Parkinson's disease and dementia, but existing reviews note highly heterogeneous protocols, lack of standardization, and that most neuroplasticity evidence derives from long-term instrumental training rather than passive listening. The patient's subjective report of improved sleep onset in this case may relate to relaxation response and cannot be inferred as structural central nervous system change.
Intestine: Small pilot studies on mantra and gastrointestinal quality of life exist, but the level of evidence is very low. In this case, epigastric discomfort showed no objective improvement, consistent with the judgment that music/mantra does not directly alter gastritis pathology.
Holy cities and rivers: Reported health benefits of holy-city visits are concentrated in psychological–spiritual empowerment and anxiety reduction rather than cure of somatic disease. There is no physiological evidence for health effects of river contact (e.g., the Ganges), and pollution-related cognitive developmental risks have been reported. This case did not involve holy-city visits or river contact, so no direct data are available; however, the literature comparison suggests that any inference equating such experiences with medical treatment requires extreme caution.
3.3 Proposed Mechanisms and Alternative Explanations
Possible shared pathways for spiritual music and mantra chanting include: modulation of respiratory rate through rhythmic vocalization, suppression of default mode network activity through focused attention, and expectancy and placebo effects arising from cultural–meaning systems. The patient's high adherence in this case may partly stem from her identification with the "spiritual" framework—a nonspecific factor that should not be overlooked when interpreting the results.
3.4 Limitations and Clinical Implications
This report is a single case without a control condition, blinding, or long follow-up (eight weeks), and objective physiological measures such as HRV or cortisol were not collected. The observed blood pressure and heart rate changes are of borderline clinical significance. Therefore, the conclusion is limited to "this patient reported subjective benefit without adverse events in this context" and cannot be extrapolated as efficacy evidence.
The clinical implication is that when patients raise or inquire about such practices, clinicians can adopt non-judgmental, open-ended communication, understand the specific practice, level of engagement, and expectations, while clearly communicating the boundaries of current evidence—namely, that these practices may serve as adjunctive stress-management tools but should not delay or replace standard evaluation and treatment of palpitations, chest tightness, or digestive symptoms.
4 Conclusion
This case report describes an individual with stress-related somatic symptoms who, alongside usual medical care, self-initiated spiritual music and mantra practice and experienced small improvements in perceived stress, heart rate, and blood pressure, without reported adverse events. Against current literature, the health-related effects of such practices are presently concentrated in autonomic modulation and subjective stress relief; there is no reliable evidence supporting their use as treatments for organic heart, brain, or intestinal disease. The "health effects" of holy-city visits and river contact should be understood as psychological–cultural experiences rather than physiological medical interventions. Future research should employ single-case experimental designs (e.g., multiple-baseline across behaviors) or randomized controlled designs, incorporate objective measures such as HRV and cortisol, and adequately control for expectancy effects to define the applicable boundaries of such practices more precisely.
Ethical statement: Written informed consent was obtained from the patient for the use of her de-identified clinical information for academic publication. The patient understands that the report may be publicly disseminated and that de-identification measures have been taken to reduce identifiability risk. This report does not involve an interventional study and did not require institutional ethics committee approval; however, the authors have followed their institution's regulations on case report publication.
References (example format; adjust to target journal style)
A controlled study on the effects of OM chanting on blood pressure, heart rate, and heart rate variability (2023).
A study on the effects of Hare Krishna mantra meditation on heart rate variability and stress indices (2024).
A randomized trial of a singing intervention on microvascular and macrovascular endothelial function in patients with coronary artery disease.
A systematic review of music interventions in Parkinson's disease, dementia, and ADHD (2024).
A small pilot study on the effects of mantra therapy on gastrointestinal quality of life (2025).
A qualitative study of psychological–spiritual empowerment among holy-site pilgrims.
An epidemiological study of Ganges basin water pollution and cognitive developmental risk in children.
CARE guidelines: consensus-based clinical case reporting guideline development (Gagnier et al.).
Practical guidance on writing case reports and case series (Wiley, 2026).
Appendix: Evidence
Tables and Mechanistic Notes
Appendix A. Music vs. Brain vs. Body:
Mechanistic Pathways
The relationship between music and the body is
not merely subjective; it involves measurable neurological, autonomic, and
endocrine responses.
A.1 Brain Engagement and Neuroplasticity
Music perception and performance recruit distributed neural networks
encompassing auditory, motor, emotional, memory, and reward circuits . Musical
training can induce structural plasticity in gray and white matter . At the
molecular level, receptive music-based interventions (listening) have been
associated with changes in gene expression linked to dopamine transport,
long-term potentiation, cognitive functions, and neuroprotection . Furthermore,
music tempo modulates cortical activity: theta band power shows consistent
modulation across different tempi, while alpha power decreases (alpha blocking)
during musical stimulation compared to silence .
A.2 Autonomic and Cardiovascular Regulation
Music with varying emphasis (crescendos vs. uniform emphasis) produces parallel
instantaneous cardiovascular responses. Vocal and orchestral crescendos
correlate with skin vasoconstriction and blood pressure changes, while rhythmic
phrases can entrain cardiovascular autonomic variables . A pilot study found
that non-musicians exhibited sustained heart rate increases and higher heart
rate variability (HRV) with music, whereas musicians showed an initial rise
followed by a reduction below control levels . The autonomic nervous system is
proposed as a central mechanism through which music exerts broad health
effects, given its links to cardiovascular, mental, and neurodegenerative
conditions .
A.3 Summary Table: Music Effects
|
Domain |
Key Finding |
Source Type |
|
Cortical activity |
Theta modulation; alpha blocking |
Pilot EEG study |
|
Gene expression |
Upregulation of
dopamine/neuroprotection genes |
Systematic review |
|
Cardiovascular |
Tempo-dependent HR/BP changes; autonomic
entrainment |
Human physiology study |
|
Autonomic tone |
Proposed central mechanism for
broad health impact |
Mechanistic review |
Appendix B. River vs. Brain: Contamination and
Cognitive Risk
There is no evidence that river water contact
or consumption confers neurological benefit. The documented river–brain link is
one of risk, primarily through environmental contamination.
B.1 Manganese and Cognitive Impairment
A study in the Puyango River Basin (Ecuador) found that children with elevated
hair manganese levels (over 2 µg/g) performed poorly on general intelligence
tests (Raven's Progressive Color Matrices). Children in the lower basin, where
river water manganese reached 970 µg/L, had the highest hair manganese and the
worst test performance .
B.2 Microbial and Chemical Risks
Quantitative microbial risk assessment of the Buriganga River (Bangladesh)
demonstrated non-negligible health burdens from E. coli and Salmonella
exposure during routine activities such as bathing and washing, with Salmonella
contributing a higher disability-adjusted life year (DALY) burden . In the
Ganga River, arsenic levels in water posed health risks for children at
multiple sites, and pharmaceutical compounds were widely detected .
B.3 Summary Table: River Exposure Risks
|
Contaminant |
Population |
Outcome |
Source |
|
Manganese |
Children |
Declined general intelligence |
Ecohealth study |
|
Salmonella spp. |
Exposed individuals |
Gastrointestinal illness burden
(DALY) |
QMRA study |
|
Arsenic |
Children (multiple sites) |
Health risk exceeding acceptable
limits |
Risk assessment |
Note: No retrieved evidence supports the hypothesis that river water
from holy cities confers cognitive or neurological benefit. Any perceived
benefit is likely attributable to psychological or spiritual factors, not
physiological mechanisms.
Appendix C. The Appendix: A Gut–Brain
Interface
The vermiform appendix is no longer considered
merely vestigial. It has emerged as a immunologically active tissue with a
potential role in the gut–brain axis, particularly relevant to Parkinson's disease
(PD).
C.1 Immunological and Microbiome Functions
The appendix contains gut-associated lymphoid tissue, generates IgA-secreting
plasma cells, and houses a biofilm that serves as a safe reservoir for
commensal bacteria, facilitating re-inoculation of the intestine after
gastrointestinal infection . It is therefore an immunological organ positioned
at the interface of the gut microbiome and host immunity.
C.2 The Appendix and Parkinson's Disease
Aggregated α-synuclein—the pathological hallmark of PD—is present in the
appendix of both PD patients and healthy individuals. The appendix contains
truncated forms of α-synuclein that are potent seeds for aggregation. Because
the appendix is innervated by the vagus nerve, it has been proposed as a site
from which α-synuclein pathology could propagate from the gut to the brain .
Some epidemiological studies have linked appendectomy to lower PD risk, though
this association remains controversial .
C.3 The Gut–Brain–Appendix Loop
A conceptual model has been proposed in which the brain, intestinal mucosa,
appendix, and microbiome interact bidirectionally. The appendix's biofilm and
immune functions may influence systemic inflammatory states relevant to mood
disorders and neurodegeneration .
C.4 Summary Table: Appendix Functions
|
Function |
Description |
Relevance |
|
Immune tissue |
IgA plasma cells; lymphoid
follicles |
Shapes gut microbiome |
|
Microbial reservoir |
Biofilm safe house for commensals |
Re-inoculation post-infection |
|
α-Synuclein reservoir |
Truncated, aggregation-prone forms
present |
Potential PD origin site |
|
Vagal innervation |
Connected to brainstem via vagus
nerve |
Gut-to-brain propagation route |
Appendix D. Integration: Why the Appendix
Matters for the Case Report
The case report described a patient with
stress-related somatic symptoms (palpitations, epigastric discomfort) and no
clear organic pathology. The appendix evidence is relevant in two ways:
Clarifying the
boundary of "gut–brain" claims: The appendix demonstrates that a genuine gut–brain axis exists,
but it operates through specific immunological and pathological mechanisms
(α-synuclein propagation, microbiome-immune interactions), not through vague
"spiritual" or "energetic" connections. This reinforces the
case report's conclusion that mantra/music practices should not be framed as
treating gut pathology.
Distinguishing symptom
perception from pathology:
The patient's epigastric discomfort showed no objective improvement despite
improved stress scores. The appendix literature underscores that structural or
inflammatory gut pathology requires specific medical evaluation; stress
reduction does not alter appendiceal α-synuclein aggregation or biofilm
composition.
Appendix D Summary:
Music engages brain networks and autonomic pathways
with measurable but modest physiological effects.
River water in contaminated settings poses documented
cognitive and infectious risks; no neurological benefit is supported.
The appendix is an immunologically active gut–brain
interface with specific relevance to Parkinson's disease pathogenesis,
underscoring that "gut–brain" language should be used with
mechanistic precision.
